Describe CancerStemCellProject/ChangjiangXu/BiostatisticsService/Consulting
#acl CancerStemCellGroup:read,write = Consulting = '''Expectations from Statistical Consulting/Analysis of Microarray Experiments ''' '''Cancer Stem Cell Network''' ''' ''' Statistical consulting for experiments in the Cancer Stem Cell Network is available by contacting Biostatistician Changjiang Xu at [[mailto:changjiang.xu@uhnres.utoronto.ca|changjiang.xu@utoronto.ca]] '''Office hours''' : '''Tuesday 3:00pm-5:00pm''' and '''Thursday 11:00am -1:00pm'''. In order to ensure that appropriate advice be given, the consulting is strongly suggested at the design stage of the experiment. Upfront required Information from researcher · Please provide '''a complete and concise summary of''' information about the experiment, · Experimental units i.e., animal strain/Humans, etc. How they were selected? · Sample preparation procedure if any? · If experiment conducted on different days/times etc? · Clear and concise '''research question'''s that you want to investigate · Specify the number of experimental conditions (factors) that you plan to study, that might influence the response variable (gene expression values in case of microarray experiments) · Number of stages that the experiment will be conducted. This will help us make sure that any factor (condition) of interest is not confounded with some non-biological factor, etc? · The type of analysis that the researcher would think would be suitable to perform · What type of chip would be used, if microarray experiment? · How many samples that researcher is planning based on budget After this upfront meeting, the statistician would take '''a week''' to make a framework for the issues and suggest the statistical feasibility for the project etc. The statistician would give recommendations for the number of samples, any other design issues, randomization, blocking etc.
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