We can migrate some of the content from the MCODE site here: http://cbio.mskcc.org/~bader/software/mcode/
attachment:MCODELogo.png
MCODE is a Cytoscape PlugIn that finds clusters (highly interconnected regions) in any network loaded into Cytoscape. Depending on the type of network, clusters may mean different things. For instance, clusters in a protein-protein interaction network have been shown to be protein complexes and parts of pathways. Clusters in a protein similarity network represent protein families.
MCODE is a relatively fast method of clustering, although it does not currently provide any statistical score on the resulting clusters. It can be used as discovery tool when analyzing a network. See the paper for more information.
Downloads
MCODE v1.2
- plugin
- requires Cytoscape v2.3.2 or later
- Javadoc
MCODE v1.1
- plugin
- requires Cytoscape v2.1
- Javadoc
Run using Java WebStart
MCODE v1.0
- plugin
- requires Cytoscape v2.0
Cytoscape
- Link to cytoscape page
User's Manual
Installation
Introduction
Advanced Techniques
Tutorials
Index
Contact
Acknowledgements
This software was originally released as a command-line-only program from the Hogue Lab. It was created by Gary Bader, currently based in the [http://www.baderlab.org Bader Lab] at the University of Toronto (formerly in the Sander Group,[http://www.cbio.mskcc.org/ Computational Biology Center, Memorial Sloan-Kettering Cancer Center], New York City)
Version 1.2 was produced by Vuk Pavlovic in the Bader Lab.
This software is made available under the LGPL (Lesser General Public License), which means that you can freely use it within your own software, but if you alter the code itself and distribute it, you must make the source code alterations freely available as well.
Please see the following paper for more information about the algorithm:
- Bader GD, Hogue CW.
- An automated method for finding molecular complexes in large protein interaction networks.
BMC Bioinformatics. 2003 Jan 13;4(1):2.